Each application must be assessed based on the following criteria:
The following are rules of thumb for guidance only:
|OEB||OEL Range µg/m3||Toxicological/Pharmacological Properties and potency||Esco Containment Technology|
|1||1000-5000||Not harmful, not irritating, low pharmacological activity||Esco Standard Pharmacon Downflow Booth with no additional engineering controls.|
|2||100-1000||Harmful, possible irritant, mid pharmacological activity||Esco Standard Pharmacon Downflow Booth with no additional engineering controls. May require additional engineering controls if the process is extremely dusty (e.g. milling).|
|3||50-100||Moderate toxicity high pharmacological activity||Esco Standard Pharmacon Downflow Booth may require additional engineering controls dependent on quantity handled and the process operation.|
|4||1-50||Toxic, corrosive, genotoxic, cytotoxic||Esco Custom Pharmacon Downflow Booth with additional engineering control:|
1.) Drum lifters
2.) Physical Barriers
3.) High containment enclosures with glove ports
4) Architectural features (e.g. airlocks/controlled access) to lower cross contamination risk
Note application would have to be assessed for suitability. Dependent on process/product the use of Isolator (glovebox) technology may be recommended.
|5||<1||Extremely toxic, may be corrosive, sensitizing||Esco strongly recommends use of Isolator (glovebox) technology at this OEL level.|
Can be incorporated as part of custom Pharmacon Downflow Booth.